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The mgR mutation has provided new insights into the function of fibrillin-1-rich microfibrils and MFS pathogenesis. It has also confirmed and extended some of the findings previously made with the mgΔ mutation . Homozygous mgR mice produce about a quarter of the normal amount of fibrillin-1 and display phenotypic features in the skeleton and.

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After careful consideration by the MGR BOA these changes will go in to effect on 5-1-2022. These changes are necessary to strengthen the genetics of the Myotonic breed. 1. Goats with one parent registered in the MGR will be registered as 50% myotonic. Goats w/o an MGR registered parent will also be registered at no greater than 50% (unless.

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M. G. Ramachandran (Actor, Politician and 3rd Chief Minister of Tamil Nadu) Fondly known by the acronym MGR, Marudhur Gopalan Ramchandran was an Indian actor who went on to become a renowned politician. He was the first popular Indian actor to serve as Chief Minister of an Indian state. MGR's career started in films.

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Elastolysis was present in all four aortic segments of mgR/mgR but was rarely observed in wild-type mice (P < .001). The diameter of the ascending aorta was larger in mgR/mgR than in wild-type mice (P = .01), but para- and infrarenal aortic diameter were even smaller in mgR/mgR mice (P < .001 and P = .01, respectively).

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M. G. Ramachandran Maruthur Gopalan Ramachandran (17 January 1917 - 24 December 1987), popularly known by his initials M.G.R., was an Indian actor, politician, and philanthropist who served as the Chief Minister of Tamil Nadu from 1977 until his death in 1987.

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The film is filled with powerful performances from its stellar cast and features unforgettable melodies contributed by the maestro M.S. Viswanathan. This engaging film continues to endear itself to audiences even today, thanks to its impeccable blend of comedy, romance, and emotion. 4. Anbe Vaa.

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Prometheus Module . Provides a Prometheus exporter to pass on Ceph performance counters from the collection point in ceph-mgr. Ceph-mgr receives MMgrReport messages from all MgrClient processes (mons and OSDs, for instance) with performance counter schema data and actual counter data, and keeps a circular buffer of the last N samples.

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Fibrillin-1 hypomorphic mice (mgR/mgR) are accepted as a model of Marfan syndrome. Phenotypic investigations of this mouse have not previously included quantification of phenotypic features and detailed examinations of the histopathology other than in the ascending aorta. Methods

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Fbn1 C1041G/+ and Fbn1 mgR/mgR data set integration, analysis, and comparison were performed by Seurat using the SCTransform integration. Marker genes for modSMCs and the MFS patient were built with the FindMarkers function via the nonparametric Wilcoxon's rank-sum test, with the requirement of minimum percentage greater than 0.25 and log2.